Table 2. Results.

	Healthy			Asthma
	Baseline	BC	% Change	Baseline	BC	% Change
FEV1 (L)	2.74±0.89	2.05±0.80	−25.1±14.6	2.64±0.45	1.62±0.36	−38.7±7.23*
FVC (L)	3.18±1.00	2.51±0.95	−21.2±12.8	3.02±0.58	2.06±0.60	−33.1±8.91*
Rlow	5.43±1.00	92.0±54.7	1730±1250	5.87±2.58	177±103	3300±2090*
Elow	6.27±1.90	10.1±4.00	61.6±37.3	8.85±3.00	17.2±11.8	82.3±74.0
Mean Lung Fgas	0.65±0.06	0.69±0.04	7.79±5.38	0.64±0.04	0.69±0.04	7.33±5.24
Fgas Vdef/Out	0.94±0.04†	1.00±0.02	6.94±4.98	0.98±0.03*†	1.03±0.05	5.87±4.86
Fgas gradient	0.0069±0.0033	0.0004±0.0020	−90.0±38.0	0.0068±0.0033	0.0004±0.0039	−105±51.8
	1.14±0.14†	0.44±0.15†	−61.0±16.3	1.04±0.14	0.54±0.16†	−46.0±25.0
	0.57±0.08	0.94±0.25	65.2±200	0.61±0.19	1.05±0.24	71.2±24.7
F Vdef		0.34±0.11			0.34±0.14

Values are means ± SD. Rlow, low-frequency resistance; Elow, low-frequency elastance; Fgas, fractional gas content; Vdef, ventilation defect; , specific ventilation inside Vdefs vs. outside; , coefficient of variation of specific ventilation; F_Vdef, fraction of total imaged volume occupied by Vdefs. % change refers to the change during bronchoconstriction compared to baseline. *P<0.05 compared to Healthy.

^†P<0.05 compared to ratio of 1.