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Proposed schematic of AHNAK, S100A10 and AnxA2 co-localization near the intracellular surface of the plasma membrane. Multiple (p11)2(AnxA2)2 complexes may bind to the C-terminal domain of AHNAK. AnxA2 binds to acidic phospholipids on the plasma membrane in a Ca2+-dependent manner, pulling AHNAK near to the plasma membrane.
