Table 4.
The number of genes with potential roles in pathogenesis and virulence in the three B. pilosicoli genomes
| Role of putative gene | 95/1000 | B2904 | WesBa |
|---|---|---|---|
| Core genes involved in lipopolysaccharide biosynthesisb |
27 |
30 |
32 |
| Chemotaxis | |||
| putative methyl-accepting chemotaxis protein |
7 |
7 |
10 |
| methyl-accepting chemotaxis protein A (mcpA) |
2 |
0 |
2 |
| methyl-accepting chemotaxis protein B (mcpB) |
8 |
11 |
11 |
| chemotaxis protein |
15 |
15 |
15 |
| Flagella |
42 |
42 |
42 |
| Adhesion and membrane protein | |||
| lipoprotein |
21 |
31 |
29 |
| variable surface protein |
3 |
4 |
4 |
| integral membrane protein |
1 |
1 |
1 |
| outer membrane protein |
25 |
25 |
23 |
| periplasmic protein |
25 |
25 |
28 |
| inner membrane protein |
75 |
83 |
83 |
| Host tissue degradation | |||
| haemolysis |
12 |
12 |
12 |
| phospholipase |
2 |
3 |
2 |
| peptidase |
44 |
48 |
48 |
| protease |
19 |
19 |
17 |
| Oxidative stress |
7 |
7 |
7 |
| Ankyrin-like protein |
31 |
34 |
35 |
| Phage and other mobile genetic elements |
46 |
109 |
100 |
| Total | 412 | 506 | 501 |
The analysis categorised the genes from the genomes of B. pilosicoli 95/1000, B2904 and WesB.
a The incomplete WesB strain genome was within one scaffold.
b Core lipooligosaccharide (LOS) biosynthesis genes.