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. 2012 Dec 28;7(12):e53449. doi: 10.1371/journal.pone.0053449

Figure 6. Immunohistochemistry staining of D2-40 for LMVD in the pleural tumors.

Figure 6

Positive immunohistochemistry staining of D2-40 was shown as brown part in each figure. Positive endothelial cells stained by anti-D2-40 antibody were recognized as lymphatic vessels. Lymphatic micro vessel density (LMVD) was counted at Section×200. LMVD in H-ES group (D) was significantly decreased compared with NS group (A) or L-ES group (B) or Bevacizumab group(C). (E): The difference of LMVD on four groups. Columns: mean value of each group, bars: ±SD. ***P<0.001, **P<0.01, *P<0.05. ns: no significant difference.