Figure 8.
Validity of the deterministic QSSA for the gene network. Plot of the macroscopic substrate concentrations of mRNA, [M], and protein, [P], versus time, as obtained by numerically solving the deterministic REs of the full network (solid lines) and the reduced REs obtained using the deterministic QSSA (open circles). The color coding and rate constant values are as in Figure 7; the value of k0is 50. The excellent agreement between the two RE solutions, implies timescale separation conditions