Table 7.
Effects of parameters on apoptosis
|
Selected parameters (Higher sensitive parameters in sensitivity analysis) |
+30% parameter value |
−30% parameter value |
||
|---|---|---|---|---|
| Parameter range | Apoptosis level (0.22512) | Parameter range | Apoptosis level (0.22512) | |
| k1+ = 1 μM-1 s-1 |
k1+ = 1.3 |
0.24831 (+10.3%) |
k1+ = 0.7 |
0.19202 (−14.7%) |
| k13+ = 5 μM-1 s-1 |
k13+ = 6.5 |
0.19674 (−12.6%) |
k13+ = 3.5 |
0.27136 (+20.54%) |
| k14+ = 0.5 μM-1 s-1 |
k14+ = 0.65 |
0.23067 (+2.46%) |
k14+ = 0.35 |
0.2172 (−3.52%) |
| k15+ = 0.5 μM-1 s-1 |
k15+ = 0.65 |
0.23067 (+2.46%) |
k15+ = 0.35 |
0.2172 (−3.52%) |
| k29+ = 0.5 μM-1 s-1 |
k29+ = 0.65 |
0.22952 (+1.95%) |
k29+ = 0.35 |
0.21911 (−2.66%) |
| k30+ = 0.5 μM-1 s-1 |
k30+ = 0.65 |
0.22952 (+1.95%) |
k30+ = 0.35 |
0.21911 (−2.66%) |
| k31+ = 1 μM-1 s-1 |
k31+ = 1.3 |
0.22952 (+1.95%) |
k31+ = 0.7 |
0.21911 (−2.66%) |
| k32+ = 0.5 μM-1 s-1 |
k32+ = 0.65 |
0.23424 (+4.05%) |
k32+ = 0.35 |
0.20999 (−6.72%) |
| k33+ = 1 μM-1 s-1 |
k33+ = 1.3 |
0.232 (+3.05%) |
k33+ = 0.7 |
0.21389 (−4.98%) |
| k34+ = 1 s-1 |
k34+ = 1.3 |
0.2392 (+6.25%) |
k34+ = 0.7 |
0.19967 (−11.3%) |
| k36+ = 1 s-1 | k36+ = 1.3 | 0.238 (+5.72%) | k36+ = 0.7 | 0.20434 (−9.23%) |