Figure 3. Surface CD16 expression on CD14⁺ monocytes before and after incubation with control or trauma patient plasma for 22 hours was decreased with CRP depletion (Trauma PC), but was not restored with CRP add-back experiments.

TGF-β receptor inhibition with SB431542 (TGF Inhibitor) and M-CSF receptor inhibition with Ki20227 (M-CSF Inhibitor) significantly reduced CD16 expression of normal monocytes. * P<0.05; nonparametric Wilcoxon test was used to determine statistical significance; n = 6 for each separate experiment.