Figure 4. Intracellular HO-1 levels and surface CD163 expression were not affected by TGF-β receptor inhibition with SB431542 (TGF Inhibitor) on CD14⁺ monocytes incubated with control or trauma patient plasma for 22 hours.

TNF-α response to LPS stimulation (10 ng/ml) was significantly diminished with SB431542. *, P<0.05; nonparametric Wilcoxon test was used to determine statistical significance; n = 6 for each separate experiment.