Figure 7.

Effect of fragmentation on isoform generation for Hs.2012. All mRNAs and ESTs in Hs.2012 were broken into fragments of 300 nt or less. The isoforms produced from these data by the algorithm (indicated at the bottom) are identical to the results prior to fragmentation (see Fig. 4). Genomic sequence (top) is shown as exons (filled boxes) and splices (angled lines; alternative splices are colored red). The alignment of mRNAs and ESTs is shown schematically by alignment intervals (horizontal lines); the ends of each expressed sequence are indicated with vertical lines. Adjacent ESTs (and isoforms) are colored differently to make it easier to distinguish them.