Table 3. The regulatory relationships between the top 5 TFs and their target genes.
TF | TargetGene | cor.1 | cor.2 | DCG |
HLF | GPR85 | 0.970975 | −0.88501 | HLF |
HLF | ING1 | 0.563873 | −0.93968 | HLF |
HLF | KLHL12 | −0.03165 | −0.99013 | HLF |
HLF | NUSAP1 | 0.227138 | −0.96687 | HLF |
HLF | NYX | 0.294478 | −0.95254 | HLF |
HLF | SULT1E1 | 0.963595 | −0.28899 | HLF |
HLF | CALCA | −0.03387 | −0.91528 | HLF |
HLF | COL15A1 | −0.053 | −0.85312 | HLF |
HLF | KLF10 | −0.01067 | −0.90286 | HLF |
NKX3-1 | NUDT21 | −0.39249 | 0.968038 | NUDT21 |
TAL1 | INPP4B | −0.5512 | 0.962619 | INPP4B |
TAL1 | PPFIA2 | −0.12643 | 0.964919 | PPFIA2 |
TAL1 | STAG2 | −0.08273 | −0.93227 | STAG2 |
E2F1 | TAL1 | −0.63941 | 0.995085 | E2F1 |
STAT4 | TAL1 | −0.54116 | 0.964951 | STAT4 |
RFX1 | TAAR3 | −0.91249 | 0.91653 | TAAR3 |
RFX1 | BCL9 | 0.046861 | 0.870466 | BCL9 |
RFX1 | LTBP4 | −0.28708 | 0.991056 | LTBP4 |
EGR3 | CBL | −0.13715 | 0.969967 | CBL |
EGR3 | CD248 | −0.47312 | 0.983806 | CD248 |
EGR3 | CDK2AP1 | 0.810745 | −0.91525 | CDK2AP1 |
EGR3 | DGKI | −0.25926 | 0.95291 | DGKI |
EGR3 | ICAM5 | 0.025647 | 0.824395 | ICAM5 |
EGR3 | KPNA4 | −0.04424 | 0.970174 | KPNA4 |
EGR3 | NCK1 | −0.69186 | 0.954629 | NCK1 |
EGR3 | TCF12 | 0.835666 | −0.89573 | TCF12 |
EGR3 | TUBA8 | −0.10359 | 0.981482 | TUBA8 |
EGR3 | BLZF1 | −0.19994 | 0.959835 | BLZF1 |
EGR3 | TDRKH | −0.9193 | 0.793759 | TDRKH |
TF represents the transcription factor. Target gene represents the target gene of transcription factor. cor.1 and cor.2 represent the coexpression correlation between the TF and the target gene in conditions 1 and 2, respectively. DCG indicates the differentially co-expressed gene of a pair of TF and target gene.