Figure 2. Changes in normalised gene expression of mitochondrial biogenic transcription factors and co-activators in response to the same 1 h cycling bout (∼164W or ∼72% VO_2peak) before and after 10-d of intensified cycle training.

A- peroxisome proliferator-activated receptor γ co-activator (PGC)-1α, B-PGC-1β, C- PGC-1 related co-activator (PRC), D- mitochondrial transcription factor A (Tfam) and E-nuclear respiratory factor 2 (NRF2). Data are mean ±SD for n = 9. pre-training exercise bout (open bars); post-training exercise bout (closed bars); Pre Ex-resting sample just prior to exercise. 3 h Post Ex -sample take 3 h after exercise; - Training, time and training x time effect P<0.001; **- training x time interaction P<0.05; * - main effect of training P<0.05; ⧫-main effect of time P<0.01.