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. 2012 Dec 28;7(12):e53329. doi: 10.1371/journal.pone.0053329

Figure 5. Suppression of NF-κB and HIF−1α by curcumin treatment.

Figure 5

(A) Representative Western blot showing NF- κB protein in the nuclear extract in samples from vehicle- and curcumin-treated mice 6 hours after laser injury. GAPDH was used as a loading control. (B) Semiquantitative analysis of the intensities of NF- κ B bands in nuclear extracts from vehicle- and curcumin-treated mice. The mean for NF- κ B in RPE–choroid complex of untreated mice was set at 100% (n = 5, *P<0.05). (C) Representative Western blot showing HIF−1α protein expression in samples from vehicle- and curcumin-treated mice on day 3 after photocoagulation. GAPDH was used as a loading control. (D) Semiquantitative analysis of the intensities of HIF−1α bands from vehicle- and curcumin-treated mice. The mean for HIF−1α in RPE–choroid complex of untreated mice was set at 100% (n = 5, **P<0.05).