Fig. 1.
Comparisons in irritable bowel syndrome (IBS) with diarrhea (IBS-D) and health of small bowel permeability [0–2 h cumulative excretion of mannitol and lactulose (both P < 0.001)] and colonic permeability [8–24 h cumulative excretion of mannitol (P = not significant) and lactulose (P = not significant)] permeability. Lactulose-to-mannose excretion ratio for the 8–24 h collection showed a numerical difference that was not significant (P = 0.106). Values are means ± SE. NHV, normal healthy volunteers.