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. 2012 Oct 19;303(12):H1418–H1425. doi: 10.1152/ajpheart.00211.2012

Fig. 4.

Fig. 4.

A: PDE5 protein detected as an intense immunoreactive band at 95 kDa in porcine coronary artery homogenates from four different animals (lanes 1–4). B and C: effect of Mel on PDE5 phosphorylation in the presence and absence of the selective MT2 receptor antagonist 4P-PDOT (10−7 M, n = 6). C shows the immunodensity of phospho-PDE5 normalized to the corresponding PDE5 protein band immunodensity. *Statistically significant difference between groups (P < 0.05).