Fig. 5.

1,25(OH)₂D₃-treated mice are more susceptible to infection with ΔespF C. rodentium mutant. A: body weight. Mice were treated with vehicle or 1,25(OH)₂D₃ intraperitoneally daily throughout infection. Each data point represents the average body weight pooled from eight mice and is expressed as the percentage of the initial body weight ± SE. Results are representative of two independent experiments. **P < 0.01; ***P < 0.001, two-way ANOVA. B: representative image of cross section of the midcolon at day 10 postinfection. Original magnification = ×200. C: ΔespF C. rodentium burden day 10 postinfection; n = 8 per group. Results are representative of 3–5 independent experiments. *P < 0.05; **P < 0.01. Mann-Whitney U-test).