. 2009 Dec 15;19(24):6970–6974. doi: 10.1016/j.bmcl.2009.10.050

Table 1.

Piperidyl benzamides SAR: aniline modifications

Compds	R	P. falciparum 3D7 strain EC₅₀, μM^a
4		6.48
5		2.16
6		1.72
7		0.114
8		0.134
9		0.146
10		0.174
11		0.054
12		0.098
13		0.048

Values are means of two experiments. Each assay plate has mefloquine, sulfadoxine and artimesinin as internal standards. The EC₅₀ values for standard compounds match the literature values.