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Anti-tumor effects of various treatments on KB tumor-bearing mice. ONT-NR, T-DNA-NR, and T-DNA(Dox)-NR were injected intratumorally in a single dose (1.5×1010 NR particles), followed by 10 min NIR irradiation or without NIR irradiation. The volumetric changes in tumor size relative to that at day 0 are plotted over time after irradiation. Data are presented as mean±SE of seven mice per group. *, P<0.05 by two-sample student’s t-test.
