TABLE 2.
Variable | Ketorolac (n=65) | Placebo (n=63) | Δ (95% CI) | P value |
---|---|---|---|---|
Postoperative pain (scale of 0-10) | ||||
0 Hours | 2.6 | 2.7 | −0.1 (−1.1 to 1.0) | .91 |
4 Hours | 2.5 | 3.0 | −0.5 (−1.2 to 0.3) | .22 |
8 Hours | 2.3 | 2.5 | −0.2 (−1.0 to 0.5) | .58 |
12 Hours | 2.0 | 2.2 | −0.2 (−0.8 to 0.5) | .58 |
16 Hours | 1.6 | 2.1 | −0.6 (−1.2 to 0.1) | .11 |
20 Hours | 1.6 | 2.3 | −0.6 (−1.3 to 0.0) | .06 |
24 Hours | 1.5 | 2.1 | −0.6 (−1.3 to 0.1) | .10 |
Morphine equivalents (mg) | ||||
24 Hours | 38 | 41 | −3 (−20 to 15) | .79 |
Discharge | 51 | 52 | −1 (−24 to 22) | .94 |
Duration of study drug infusion (h) | 23.3 | 22.7 | 0.5 (−0.4 to 1.4) | .25 |
Blood transfusion, No. (%) | 0 | 0 | 0.00 (−0.06 to 0.06) | >.99 |
Urine output (mL) | 3200 | 4500 | −1300 (−2000 to −500) | .001 |
Time to oral fluids (h) | 3.3 | 3.7 | −0.5 (−1.5 to 0.5) | .32 |
Time to general diet (h) | 14 | 16 | −2.0 (−5.2 to 1.1) | .20 |
Time to flatus (h) | 17 | 19 | −1.7 (−6.6 to 3.3) | .50 |
Time to ambulation (h) | 9.7 | 12 | −2.0 (−4.2 to 0.3) | .09 |
Postoperative weight gain (kg) | 85 | 86 | −1.1 (−7.0 to 4.9) | .72 |
CI = confidence interval.
Data are presented as mean unless otherwise indicated.