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. 2013 Jan;182(1):180–191. doi: 10.1016/j.ajpath.2012.09.010

Figure 3.

Figure 3

Phagocytic function and in vivo response to antigenic stimulation. A: Phagocytosis (1.22 μm magnet uptake) assay reveals that GF mice have significantly more phagocytic activity than CL mice (P = 0.031). Representative of two independent experiments (n = 3 per group). B: KC frequency in CL and GF mice before and 24 hours after treatment with 100 ng of flagellin (FLA) reveals that FLA treatment does not cause significant differences in KC frequency. Representative of two independent experiments (n = 3 to 4 per group). C: Monocyte frequency (CD11b+Ly6C+ NPCs) 24 hours after FLA challenge results in greater liver monocyte influx in GF mice compared with CL mice. Representative of two independent experiments (n = 3 to 4 per group). Adult CL, GF, and AVMN mice were used. *P < 0.05, ***P < 0.01.