Figure 2.

Frequency distributions of peripheral blood parasitemia, plasma Plasmodium falciparum histidine-rich protein 2 (PfHRP2) concentrations, and modeled fitted PfHRP2, according to malaria clinical group (1 = healthy rapid diagnostic test [RDT]–negative controls, 2 = asymptomatic carriers, 3 = uncomplicated malaria, 4 = severe malaria, 5 = severe malaria). The fitted PfHRP2 distributions (right column) show the modeled PfHRP2 distributions with the underlying contributing PfHRP2 distributions of different diagnostic groups (dotted lines), composed of RDT-negative controls (light green), asymptomatic carriers (green), and patients with uncomplicated malaria (blue turquoise) or severe malaria (bright blue and purple).