Table 2.
VDRs and VDRl mRNA concentration in female and male population of group B-AIS
| |
|
Group B (15 females) |
Group B (5 males) |
U-Mann Whitney |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sample | Isoform | Average | Median | Range | St. dev | Average | Median | Range | St. dev | p |
| B1 |
VDRl |
0 |
0 |
0 |
|
0 |
0 |
0 |
|
|
| VDRs |
240 |
150 |
11-746 |
300.5 |
7 |
7 |
2-13 |
7.3 |
0.09 |
|
| B2 |
VDRl |
0 |
0 |
0 |
|
0 |
0 |
0 |
|
|
| VDRs |
271 |
189 |
35-663 |
262 |
36 |
36 |
33-40 |
4.6 |
0.06 |
|
| C1 |
VDRl |
0 |
0 |
0 |
|
0 |
0 |
0 |
|
|
| VDRs |
1317 |
92 |
24-6193 |
2726.9 |
142 |
142 |
4-280 |
195.6 |
0.43 |
|
| C2 |
VDRl |
57 |
57 |
57 |
|
0 |
0 |
0 |
|
|
| VDRs |
3490 |
82 |
7-34119 |
10762 |
101 |
101 |
14-188 |
123.4 |
0.83 |
|
| M1 |
VDRl |
33 |
36 |
4-58 |
23.4 |
176 |
176 |
4-347 |
242.1 |
0.83 |
| VDRs |
268 |
50 |
6-1649 |
561 |
290 |
375 |
8-487 |
250.4 |
0.95 |
|
| M2 |
VDRl |
49 |
43 |
3-132 |
43.6 |
77 |
77 |
37-117 |
56.8 |
0.79 |
| VDRs |
641 |
17 |
1-4902 |
1612.5 |
372 |
165 |
44-906 |
466.8 |
0.50 |
|
| Blood | VDRl |
1215 |
1215 |
4-2427 |
1713.4 |
833 |
833 |
833 |
|
|
| VDRs | 695 | 695 | 30-1361 | 941.3 | 2621 | 2621 | 1800-3442 | 1160.6 | 0.04 | |
Comparison of QRT-RTPCR results obtained from homonymous tissue samples (B1-bone from concavity, B2-bone from convexity, C1-cartilage from concavity, C2-cartilage from convexity, M1-muscles from concavity, M2-muscles from convexity, blood) between females (n=15) and males (n=5) in group B – Adolescent Idiopathic Scoliosis , p<0,05 was considered as a statistically significant (nonparametric Mann Whitney U test).