Table 3.
Likelihood ratio and predictive value (%) of patterns of symptoms and signs with and without concomitant variables, for the presence of objective cardiac structural and functional parameters. Area under the ROC curve for the classification with and without concomitants
| Pattern of symptoms and signs |
Pattern of symptoms and signs with concomitant variables |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcomes prevalence | 1 | 2 | 3 | 1 | 2 | 3 | |||
| N (%) | LR (PV) | LR (PV) | LR (PV) | AUC | LR (PV) | LR (PV) | LR (PV) | AUC | |
| Outcomes | |||||||||
| Left ventricular systolic dysfunction | 39 (3.5) | 3.6 (11.5) | 1.1 (3.9) | 0.6 (2.3) | 64.5 | 3.4 (11.1) | 1.1 (3.7) | 0.6 (2.2) | 65.1 |
| Left ventricular dilation | 55 (4.9) | 4.1 (16.8) | 1.2 (5.6) | 0.6 (2.8) | 67.4 | 4.4 (17.7) | 1.0 (4.9) | 0.5 (2.5) | 69.5 |
| Diastolic dysfunction | 161 (14.5) | 3.6 (38.0) | 1.6 (21.9) | 0.6 (9.8) | 65.2 | 3.6 (38.1) | 1.7 (22.5) | 0.5 (7.6) | 69.3 |
| Left ventricular hypertrophy | 145 (12.9) | 3.4 (33.6) | 1.3 (16.4) | 0.7 (9.4) | 63.0 | 3.5 (34.5) | 1.4 (17.8) | 0.5 (7.4) | 67.5 |
| Left atrium dilation | 185 (16.6) | 2.2 (30.8) | 1.5 (23.8) | 0.7 (13.1) | 60.0 | 2.4 (33.0) | 1.5 (23.0) | 0.6 (11.5) | 62.9 |
| Valvular disease | 31 (2.8) | 4.0 (10.6) | 0.7 (1.9) | 0.7 (2.1) | 63.0 | 3.4 (9.0) | 1.5 (4.3) | 0.4 (1.2) | 71.1 |
| Any of the above | 322 (29.6) | 2.6 (52.4) | 1.5 (38.5) | 0.8 (24.2) | 60.0 | 3.1 (56.9) | 1.6 (39.9) | 0.6 (20.7) | 64.5 |
| High BNP(≥100 pg/ml) | 40 (6.3) | 3.6 (19.4) | 1.8 (10.7) | 0.4 (2.6) | 72.9 | 3.4 (18.2) | 1.7 (9.9) | 0.2 (1.7) | 75.1 |
AUC, area under the curve; LR, likelihood ratio; PV, predictive value; ROC, receiver operating characteristic.