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. 2012 Nov 23;2(6):e001624. doi: 10.1136/bmjopen-2012-001624

Table 2.

Univariate and multivariate Cox proportional hazards models for overall survival

Univariate analysis
Multivariate analysis
HR 95% CI p Value HR 95% CI p Value
Age (per 10 years) 1.09 0.99 to 1.03 0.46 1.19 0.92 to 1.54 0.19
Sex
 Male 1 1
 Female 1.17 0.61  to 2.21 0.64 1.30 0.61 to 2.78 0.50
Race 0.59 0.40
 White 1 1
 Asian 0.91 0.22  to  3.77 0.90 0.91 0.18 to  4.49 0.90
 Black 2.21 0.53 to  9.17 0.27 3.76 0.80 to 17.57 0.09
Histological type
 Adenocarcinoma 1 1
 Squamous cell 1.63 0.92 to 2.88 0.10 1.14 0.53 to  2.43 0.74
Pathological stage 0.004 0.001
 I 1 1
 II 2.42 1.08  to  5.38 0.03 2.65 1.13  to  6.22 0.03
 III 4.01 1.88  to  8.55 <0.0005 5.14 2.23 to 11.82 <0.0005
 IV 2.14 0.27  to  16.94 0.47 0.94 0.11  to  8.10 0.96
Neoadjuvant therapy
 No 1 1
 Yes 1.78 1.02 to  3.11 0.04 2.65 1.38 to 5.09 0.003
Percent (per 10%) 1.04 0.95  to 1.14 0.42 1.13 1.01 to 1.26 0.03