Table 5.

Possible parameter values for signaling over a distance of 10 μm using harmonic signals (closed geometry).

Parameter	Approx. max. value	Comments
Frequency	0.5 Hz	For Vmax = 100 μM s−1
	0.05 Hz	For Vmax = 10 μM s−1
	<0.01 Hz	For Vmax = 1 μM s−1
Amplitude	10–20 μM	For Vmax = 100 μM s−1 and f = 0.5 Hz. Can be higher for lower frequencies; lower Vmax implies lower amplitude
Maximum background concentration	1–2 μM	For cmax/ctrough = 10 and depending on Vmax