Table 1.
Characteristics of the study sample
| HIV comparison | HIV/HCV comparison | HCV comparison | |||||||
|---|---|---|---|---|---|---|---|---|---|
| HIV (n=239) |
NHANES (n=717) |
p | HIV/ HCV (n=182) |
NHANES (n=546) |
p | HCV (n=167) |
NHANES (n=501) |
p | |
| Age, mean (SD) | 44.5 (9.5) | 44.5 (9.5) | >.99 | 49.5 (7.1) | 49.5 (7.1) | >.99 | 51.2 (7.7) | 51.2 (7.7) | >.99 |
| Male | 165 (69%) | 495 (69%) | >.99 | 116 (64%) | 348 (64%) | >.99 | 101 (60%) | 303 (60%) | >.99 |
| Body Mass Index, mean (SD) | 28.2 (5.8) | 29.1 (5.9) | 0.03 | 25.9 (5.5) | 30.0 (6.4) | <.001 | 29.7 (6.9) | 30.1 (7.0) | 0.38 |
| Ethnicity | |||||||||
| White/Other | 125 (52%) | 375 (52%) | >.99 | 46 (25%) | 138 (25%) | >.99 | 77 (46%) | 231 (46%) | >.99 |
| Black | 88 (37%) | 264 (37%) | 94 (52%) | 282 (52%) | 60 (36%) | 180 (36%) | |||
| Hispanic | 26 (11%) | 78 (11%) | 42 (23%) | 126 (23%) | 30 (18%) | 90 (18%) | |||
| Marital status | |||||||||
| Single | 154 (64%) | 153 (21%) | <.001 | 104 (57%) | 102 (19%) | <.001 | 82 (48%) | 80 (16%) | <.001 |
| Married | 46 (19%) | 439 (61%) | 34 (19%) | 330 (60%) | 52 (31%) | 304 (61%) | |||
| Divorced/widowed | 39 (16%) | 125 (18%) | 44 (24%) | 114 (21%) | 33 (20%) | 117 (23%) | |||
| Current smoker | 104 (43%) | 195 (27%) | <.001 | 118 (65%) | 151 (28%) | <.001 | 85 (51%) | 129 (26%) | <.001 |
| Current or former cocaine or heroin use | 81 (34%) | 85 (19%) | <.001 | 148 (82%) | 75 (22%) | <.001 | 105 (63%) | 67 (20%) | <.001 |
| Hypertensiveb | 91 (38%) | 136 (19%) | <.001 | 88 (48%) | 136 (25%) | <.0001 | 108 (65%) | 134 (27%) | <.001 |
| Diabeticc | 18 (7%) | 55 (8%) | 0.94 | 25 (14%) | 85 (16%) | 0.55 | 47 (28%) | 89 (18%) | 0.004 |
| On lipid medications | 57 (24%) | 69 (10%) | <.001 | 9 (5%) | 82 (15%) | <.0001 | 23 (14%) | 86 (17%) | 0.30 |
| On blood pressure medications | 45 (19%) | 114 (16%) | 0.29 | 45 (25%) | 138 (25%) | 0.88 | 71 (43%) | 135 (27%) | <.001 |
| On glucose medications | 9 (4%) | 21 (3%) | 0.52 | 10 (5%) | 35 (6%) | 0.66 | 33 (20%) | 42 (8%) | <.001 |
| Lipid Profile (mg/dL), mean (SD) | |||||||||
| Total cholesterol (TC) | 192.6 (39.1) | 201.5 (40.3) | 0.003 | 164.1 (41.1) | 204.8 (37.4) | <.001 | 168.9 (43.4) | 205.8 (41.4) | <.001 |
| High density lipoprotein cholesterol (HDL) | 45.2 (14.2) | 51.1 (16.0) | <.001 | 44.9 (16.6) | 52.7 (15.7) | <.001 | 46.6 (16.6) | 52.1 (15.1) | <.001 |
| Non-HDL | 147.5 (37.2) | 150.4 (43.0) | 0.30 | 119.2 (38.5) | 152.1 (40.5) | <.001 | 122.3 (37.7) | 153.6 (42.8) | <.001 |
| 10-yr General Framingham Risk Score % | 8.9 (7.5) | 7.9 (7.4) | 0.08 | 12.0 (8.7) | 11.1 (9.0) | 0.23 | 14.2 (8.9) | 11.6 (8.4) | <.001 |
| Vascular age difference | 7.2 (10.0) | 4.5 (10.0) | <.001 | 9.6 (12.1) | 7.0 (12.1) | 0.01 | 12.5 (11.6) | 7.5 (12.0) | <.001 |
SD: Standard deviation.
a
Hypertension: systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, or self-report of current or former diagnosis of hypertension or pharmacotherapy for hypertension;
b
Diabetes: fasting glucose ≥ 126 mg/dL, random or oral glucose tolerance ≥ 200 mg/dL, or self-report of current or former diagnosis of diabetes or pharmacotherapy for diabetes