Table 2.
Disease characteristics of the virally infected sample
| Disease characteristics | HIV only (n=239) |
HCV only (n=167) |
HIV/ HCV (n=182) |
P |
|---|---|---|---|---|
| HCV disease characteristics | ||||
| Degree of fibrosis (liver biopsy) | ||||
| None | 11 (6%) | 15 (8%) | 0.008 | |
| Low (score of 1 or 2) | 65 (34%) | 23 (12%) | ||
| Mild (score of 3 or 4) | 35 (18%) | 20 (10%) | ||
| Cirrhosis (score of 5 or 6) | 10 (5%) | 11 (6%) | ||
| No biopsy performed | 60 (33%) | 127 (65%) | ||
| HCV genotype 11 | 133 (81%) | 133 (69%) | 0.06 | |
| HCV viral load2 | 6.62 (6.9) | 6.84 (7.2) | 0.11 | |
| HCV treatment | 83 (46%) | 42 (21%) | <.0001 | |
| HIV disease characteristics | ||||
| HIV risk behavior3 | ||||
| Heterosexual contact | 114 (48%) | 69 (40%) | <.0001 | |
| MSM | 103 (43%) | 6 (3%) | ||
| IDU | 8 (3%) | 74 (43%) | ||
| MSM and IDU | 3 (1%) | 10 (6%) | ||
| Other | 11 (5%) | 11 (6%) | ||
| Duration of HIV (mean years) | 8.11 (6.4) | 11.66 (6.4) | <.0001 | |
| CD4 count (cells/μL) (mean) | 518 (330) | 410 (311) | 0.001 | |
| Nadir CD4 count (cells/μL) (mean) | 224 (211) | 194 (196) | 0.13 | |
| HIV viral load, mean | 4.24 (4.7) | 4.41 (4.9) | 0.25 | |
| HIV viral load < 50 copies/mL | 150 (64%) | 89 (49%) | 0.003 | |
| HIV antiretroviral characteristics | ||||
| Currently on antiretrovirals | 189 (79%) | 125 (69%) | 0.01 | |
| Cumulative HAART exposure in years (SD) | 4.36 (3.6) | 3.86 (3.5) | 0.15 | |
| Current HAART includes a PI | 99 (52%) | 68 (54%) | 0.72 | |
| Current HAART includes a NRTI | 152 (80%) | 111 (89%) | 0.05 | |
| Current HAART includes an NNRTI | 95 (50%) | 61 (49%) | 0.80 | |
| HIV viral load < 400 copies/mL | 163 (86%) | 98 (78%) | 0.07 | |
| At least 95% treatment adherence to HAART4 | 143 (93%) | 87 (90%) | 0.28 |
1
N=163 (HCV), n=125 (HIV/HCV);
2
N=165 (HCV), n=142 (HIV/HCV);
3
n=170 (HIV/HCV);
4
N=153 (HIV), n=97 (HIV/HCV).