TABLE 1.

Effects of α7 nAChR PAMs of NS1738 (30 mg/kg i.p.) and PNU-120596 (4 mg/kg i.p.) on mechanical sensitivity in naive mice

The two α7 nAChR PAMs were given i.p. to animals; their withdrawal thresholds (g) were measured 30 minutes later. Data are presented as the mean ± S.E. of six mice.

	Contralateral	Ipsilateral
Vehicle	5.33 ± 0.84	4.67 ± 0.67
NS1738	5.50 ± 0.96	5.00 ± 0.57
PNU-120596	4.33 ± 0.61	4.67 ± 0.42