TABLE 2.

NS1738 blocks PNU-120596’s antinociceptive effect in the formalin test

Mice were treated with NS1738 (30 mg/kg i.p.) 15 minutes before an active dose of PNU-120596 (4 mg/kg i.p.) and were tested 15 minutes after the second injection in the formalin test. The total time spent licking the right hind paw was measured during the late phase. Data are presented as the mean ± S.E.M for each group of six to eight mice.

	Paw Licking (Phase II)
Vehicle	173.85 ± 8.06
NS1738	176.16 ± 7.10
PNU-120596	65 ± 5.06
NS + PNU	130.44 ± 11.46

NS, NS1738; PNU, PNU-120596.