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. 2012 Dec 17;2012:470247. doi: 10.1155/2012/470247

(b) Prenatal intervention studies using the 2009 IOM gestational weight gain recommendations

Reference, Sample characteristics Treatment    Gestational weight gain (GWG) (kg) Maternal weight retention
postpartum (PP) (kg)
Infant birth weight (g)
Control Intervention Control Intervention P value Control Intervention P value Control Intervention P value
Cavalcante et al. [70]
  
Design
RCT  
  
N = 71
C = 37
I = 24  
Country  
Brazil  
Ethnicity  
NA  
Age  
NA  
Parity  
NA  
SES  
Low SES  
Prepreg BMI  
C = 23.4 ± 3.8
I = 24.1 ± 4.5  
Gestational age at recruitment  
18–20 weeks  
Duration of study  
until end of pregnancy
Sedentary during pregnancy Physical activity:  
Supervised exercise program  
  
Frequency  
3/week
Intensity  
70% pred HR max  
Duration  
50 min  
Type  
Water aerobic  
  
Delivered by trained instructors
At delivery  
15.1 ± 1.6  
  
Adherence to IOM 
NA
At delivery  
14.3 ± 2.1  
  
Adherence to IOM  
NA
0.38 NA NA 3,313 ± 656  
  
<2,500 g
n = 2 (37%)
3,222 ± 563  
  
<2,500 g
n = 3 (33%)
0.54  
  
  
0.44

Barakat et al. [69]
  
Design
RCT  
  
N = 160
C = 80
I = 80  
Country  
Spain  
Ethnicity:
NA  
Age:
C = 29.5 ± 3.7
I = 30.4 ± 2.9  
Parity  
C = 57% nulliparous
I = 72% nulliparous  
SES  
C = 13% high school
I = 26% high school  
Prepreg BMI:
C = 23.4 ± 0.5
I = 24.3 ± 0.5  
Gestational age at recruitment  
12-13 weeks  
Duration of study  
until end of pregnancy
Continue usual daily activities Physical activity:  
Supervised exercise program  
  
Frequency  
3/week
Intensity
60% HR max  
Duration  
35–40 min  
Type  
Muscle strengthening and toning program
At delivery  
12.4 ± 3.4  
  
Adherence to 2009 IOM  
NA
At delivery  
11.5 ± 3.7  
  
Adherence to 2009 IOM  
NA
>0.1 NA NA 3,307 ± 477  
  
<2,500 g
n = 4 (6%)  
  
>4,000 g
n = 7 (10%)
3,165 ± 411  
  
<2,500 g
n = 4 (6%)  
  
>4,000 g
n = 1 (1%)
>0.1  
  
  
>0.1  
  
  
>0.1

Barakat et al. [72]
  
Design
RCT  
  
N = 83
C = 43
I = 40  
Country  
Spain  
Ethnicity
NA  
Age
C = 31 ± 3
I = 32 ± 4  
Parity  
C = 49% nulliparous
I = 65% nulliparous  
SES  
C = 14% >high school
I = 83% >high school  
Prepreg BMI:
C = 23.0 ± 2.9
I = 22.7 ± 2.8  
Gestational age at recruitment  
6–9 weeks  
Duration of study  
until end of pregnancy
Continue usual daily activities Physical activity:  
Supervised exercise program  
  
Frequency  
3/week  
Intensity  
≤70% HR max  
Duration  
35–45 min  
Type  
aerobic class (2/week)
aquatic activities (1/week)
At delivery  
13.8 ± 3.1  
  
Adherence to 2009 IOM  
NA
At delivery  
12.5 ± 3.2  
  
Adherence to 2009 IOM  
NA
>0.05 NA NA 3,465 ± 411 3,404 ± 465 >0.05

Haakstad and Bø [67]
  
Design
RCT  
  
N = 105
C = 53
I = 52  
Country  
Norway  
Ethnicity  
NA  
Age  
C = 30.3 ± 4.4
I = 31.2 ± 3.7  
Parity  
100% nulliparous  
SES  
C = 85% college/university
I = 85% college/university  
Prepreg BMI  
C = 23.9 ± 4.7
I = 23.8 ± 3.8  
Gestational age at recruitment  
C = 18.0 ± 4.3
I = 17.3 ± 4.1  
Duration of study  
12 weeks
Continue usual daily activities Physical activity:  
Supervised exercise program  
  
Frequency  
≥2/week  
Intensity  
12–14 RPE  
Duration  
60 min  
Type  
Aerobic dance  
  
Women were asked to exercise 30 min/day on other days  
  
Delivered by certified aerobic instructors
At 36–38 weeks  
13.8 ± 4.0  
  
  
  
  
  
  
  
Adherence to 2009 IOM 
62% did not exceed
At 36–38 weeks  
13.0 ± 4.0  
  
If attendance to all ex sessions   
(2/week, n = 24)
11.0 ± 2.0  
  
Adherence to 2009 IOM  
67%  
  
if ex 2/week
0% did not exceed
0.31  
  
  
  
0.01  
  
  
  
  
  
0.59  

0.006
At 8.1 ± 1.5 w PP  
3.3 ± 4.1
At 7.1 ± 1.6  
we PP  
3.3 ± 3.9  
  
if ex sessions 2/week  
0.8 ± 1.7
0.93  
  
  
  
0.001
NA NA

Nascimento et al.
[68]
  
Design
RCT  
  
N = 82
C = 42
I= 40  
Country  
Brazil  
Ethnicity  
NA  
Age  
C = 30.9 ± 5.9
I = 29.7 ± 6.8  
Parity  
C = 24% nulliparous
I = 30% nulliparous  
SES  
C = 38% >12 yr of school
I = 43% >12 yr of school
Prepreg BMI  
C = 36.4 ± 6.9
I = 34.8 ± 6.6  
Gestational age at recruitment 
C = 17.8 ± 3.7
I = 17.6 ± 4.2  
Duration of study  
until end of pregnancy
Standard prenatal care Physical activity:  
Supervised exercise program  
  
Frequency  
1/week  
Intensity  
HR < 140  
Duration  
40 min  
Type  
Aerobic dance  
  
Women were asked to exercise 5/week at home  
  
Other:  
women were counseled on recommended GWG  
  
Delivered by trained physical
therapists
At final visit  
11.5 ± 7.4  
OB
= 10.9 ± 7.6  
OW
=16.4 ± 3.9  
  
Adherence to 2009 IOM  
43% did not exceed
At final visit  
10.3 ± 5.0  
OB
= 10.4 ± 5.6  
OW
= 10.0 ± 1.7  
  
Adherence to 2009 IOM  
52% did not exceed
0.54  
   
0.76  
  
0.001  
  
  
  
0.43
NA NA 3,228 ± 591  
  
SGA
n = 1 (3%)  
  
LGA
n = 8 (24%)
3,267 ± 700  
  
SGA
n = 2 (6%)  
  
LGA
n = 8 (24%)
0.79  
  
  
NS  
  
  
NS

Abbreviations: RCT: randomized controlled trial; N: total number; C: control group; I: intervention group; SES: socioeconomic status; prepreg BMI: body mass index prior to pregnancy; IOM: Institute of Medicine; NA: non available; NS: non significant, NW: normal weight; OW: overweight; OB: obese.