Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
ESI-09 inhibits EPAC2-mediated insulin secretion in INS-1 cells. INS-1 cells were stimulated with vehicle or 10 µM 007-AM after pretreatment with the indicated concentrations of ESI-09. Bars represent mean ± S.D. (n = 3). #Significantly higher than vehicle group (P < 0.05). *Significantly lower that 007-AM-stimulated group (P < 0.05).
