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IHC staining of p-PKA-Cγ (A) and p-CREB (B) IEC-positive cells between patients with inactive UC and controls (nuclear staining). Quantification of the percentage positive IECs in each biopsy showed significantly increased percentages of p-PKA-Cγ–positive (***p = 0.0003) (C) and p-CREB–positive (****p = 0.0025) (D) IECs in biopsies from patients with inactive UC compared with control biopsies.
