Table 2.
Effect of DACT1 on the gene expression profiles of cancer pathways.
| Genbank accession | Gene symbol | Gene name | Gene function | Fold change (DACT1/control) |
|---|---|---|---|---|
| NM_000633 | BCL2 | B-cell CLL/lymphoma 2 | Antiapoptosis | −1.9 |
| NM_138578 | BCL-XL | BCL2-like 1 | Antiapoptosis | −1.6 |
| NM_000584 | IL8 | Interleukin-8 | Angiogenesis | −1.6 |
| NM_000594 | TNFα | Tumor necrosis factor (TNF superfamily, member 2) | Angiogenesis | −1.5 |
| NM_002608 | PDGFB | Platelet-derived growth factor β polypeptide (simian sarcoma viral [v-sis] oncogene homolog) | Proliferation and angiogenesis | −1.5 |
| NM_003376 | VEGFA | Vascular endothelial growth factor A | Proliferation and angiogenesis | −1.5 |