Table 3.
Variable | Nonmethylated (n = 145) | % | Methylated (n = 60) | % | P |
---|---|---|---|---|---|
Age (mean ± SD) | 58 ± 11.5 | 55 ± 13.9 | 0.07 | ||
Sex | |||||
M | 102 | 70.3 | 37 | 61.7 | 0.23 |
F | 43 | 29.7 | 23 | 38.3 | |
Helicobacter pylori infection | |||||
Negative | 66 | 66.7 | 20 | 64.5 | 0.83 |
Positive | 33 | 33.3 | 11 | 35.5 | |
Lauren classification | |||||
Diffuse or Mixed | 25 | 17.4 | 8 | 13.6 | 0.51 |
Intestinal | 119 | 82.6 | 51 | 86.4 | |
Location | |||||
Cardiac | 30 | 20.7 | 11 | 18.3 | 0.70 |
Non-cardiac | 115 | 79.3 | 49 | 81.7 | |
Differentiation | |||||
Poor | 78 | 64.5 | 40 | 76.9 | 0.11 |
Well or moderate | 43 | 35.5 | 12 | 23.1 | |
Lymph node metastasis | |||||
Negative | 37 | 31.1 | 5 | 11.9 | 0.015 |
Positive | 82 | 68.9 | 37 | 88.1 | |
Tumor Size | |||||
T1–T2 | 34 | 29.6 | 4 | 10.0 | 0.013 |
T3–T4 | 81 | 70.4 | 36 | 90.0 | |
Distant metastasis | |||||
Negative | 95 | 77.9 | 27 | 62.8 | 0.05 |
Positive | 27 | 22.1 | 16 | 37.2 | |
TNM stage | |||||
I–II | 51 | 38.1 | 6 | 11.3 | <0.0005 |
III–IV | 83 | 61.9 | 47 | 88.7 |