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. 2013 Jan;98(1):23–30. doi: 10.3324/haematol.2012.067611

Figure 3.

Figure 3.

Reduced thymic generation of Tcon and Treg in ATG-G treated patients. Representative gate of (A) naïve conventional CD4 T cells (naïve Tcon; CD25lowFOXP3-CD45RA+) and (B) naïve regulatory CD4 T cells (naïve Treg; CD25highFOXP3+CD45RA+) for identification of CD31+ recent thymic emigrants (RTE). The graphs illustrate mean values of absolute numbers of cells/μL ± standard error of mean (SEM) before (pre) and after transplantation of (C) TconRTE and (D) TregRTE. Differences in cell counts between patients treated or not with ATG-G were statistically evaluated using the Mann-Whitney test. *P<0.05; **P<0.01; ***P<0.005.