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. 2012 Aug 9;7:49. doi: 10.1186/1750-1172-7-49

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Copyright ©2012 van Beek et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Evaluation of the BIOCHIP mosaic for the routine diagnosis of autoimmune bullous diseases. A large panel of consecutive sera (n = 453) from patients with suspected autoimmune bullous disease was subjected to both the BIOCHIP mosaic (black columns) and the routine multi-step procedures of the autoimmune laboratory of the department of dermatology, Luebeck (grey columns; detailed in [38]). Obtained diagnoses were grouped into BP (bullous pemphigoid), “pemphigoid” diseases (including linear IgA disease, p200-pemphigoid, mucous membrane pemphigoid and dermatitis herpetiformis), PV/PNP (pemphigus vulgaris/ paraneoplastic pemphigus), PF (pemphigus foliaceus), and PG (pemphigoid gestationis). PNP and “pemphigoid” sera are further specified in Table 4.