Table 3.
Characteristics of pemphigus-related substrates used in the BIOCHIP mosaic
| Disease | Desmoglein 1 | Desmoglein 3 |
|---|---|---|
|
Pemphigus vulgaris |
33/65 |
64/65 |
| Sensitivity |
52.3 |
98.5 |
| 95%CI |
39.5% to 64.9% |
91.7% to 100% |
| Specificity |
100 |
99.6% |
| 95%CI |
98.6% to 100% |
98.6% to 100% |
|
Pemphigus foliaceus |
45/50 |
3/50 |
| Sensitivity % |
90% |
not applicable |
| 95%CI |
78.2% to 96.7% |
|
| Specificity % |
100% |
99.6% |
| 95%CI |
98.6% to 100% |
97.9% to 100% |
|
Linear IgA disease |
0/18 |
0/18 |
|
Bullous pemphigoid |
0/42 |
1/42 |
|
HBD |
0/100 |
0/100 |
| NISD | 0/97 | 0/97 |
HBD, healthy blood donors; NISD, non-inflammatory skin diseases; 95%CI, 95% confidence intervals.