Table 5.
Outcomes of open and laparoscopic pancreatic surgery in international centres of excellence
| Authors | Study design | Patients, n | Type of procedure | Operation time, min | Blood loss, ml | Conversion rate | Hospital stay, days | Morbidity, n (%) | Mortality, n (%) | Spleen preservation in DP |
|---|---|---|---|---|---|---|---|---|---|---|
| Cameron et al. (2006)28 | Retrospective observational cohort study | 1970s: 2 1980s: 63 1990s: 587 2000s: 347 | Open PD | 1970s: 528 1980s: 378 1990s: 366 2000s: 330f | 1970s: 1090 1980s: 900 1990s: 700 2000s: 700f | N/A | 1980s: 17 1990s: 11 2000s: 9f | 41% | 10 (1%) | N/A |
| Winter et al. (2006)2 | Retrospective observational cohort study | 1175 | Open PD | 380 (200–790)e | 800 (150–15 000)e | N/A | 9 (4–375)e | 415 (38%) | 26 (2%) | N/A |
| Diener et al. (2011)27 | Randomized controlled trial | 352 | Open DP | 190.0 ± 80.5c | NR | N/A | 15.4 ± 14.7c | 157 (45%) | 3 (1%) | 59 (17%) |
| Gagner et al. (2009)8 | Review | 146 | Laparoscopic PD | 439.3 (284–660)d | 142.8 (50–770)d | 46% | 18 (7–39)d | 23 (16%) | 2 (1.3%) | N/A |
| Borja-Cacho et al. (2009)7 | Systematic review | 806 | Laparoscopic DP | 199.1 ± 83.5c | 235.7 ± 42.9c | 74 (9.2%) | 6.6 ± 4.1c | 284 (37.6%) | 2 (0.2%) | 400 (49.6%) |
| Present study | Systematic review | PD: 131 DP: 85 | PD and DP | PD: 510 ± 107c DP: 281 ± 102c | PD: 440 ± 254c DP: 251 ± 317c | PD: 22 (16.4%)a DP: 5 (7.7%)b | PD: 15.9 ± 16.7c DP: 6.0 ± 2.0c | PD: 51 (38.9%) DP: 15 (17.6%) | PD: 3 (2.3%) DP: 0 | PD: N/A DP: 74 (87.1%) |
a
Of 134 intended robot-assisted procedures.
b
Data for 65 patients.
c
Mean ± standard deviation.
d
Mean (range).
e
Median (range).
f
Median.
PD, pancreatoduodenectomy; DP, distal pancreatectomy; N/A, not applicable; NR, not reported.