Table 1.

Baseline characteristics of patients submitted to hepatic resection for hepatocellular carcinoma (HCC) with portal hypertension (PHTN) or without portal hypertension (no PHTN)

Preoperative data	160 no-PHTN	P	63 PHTN
Gender M/F	112/48 70%/30%	NS	45/18 71%/29%
Age (years)	66.8 ± 9.6	NS	65.3 ± 9.5
Aetiology (HCV, HBV or other)	91; 29; 40 57%; 18%; 25%	NS	44; 9; 10 70%; 14%; 16%
Liver cirrhosis	153 (96%)	NS	63 (100%)
Child–Pugh class A	100%	NS	100%
MELD	7.9 ± 1.4	0.001	9.5 + 2.8
BCLC (A1; A2; A3)	160/0/0	0.001	0/37/26
Varices (F0)	0%	0.001	48 (76%)
Fibrosis (Ishak)	5.1 ± 1.2	0.001	5.9 ± 0.4
Bilirubin level (mg/dl)	0.80 ± 0.36	0.001	1.39 ± 1.55
Abnormal bilirubin (>1 mg/dl)	28 (19%)	0.001	36 (57%)
Albumin level (g/dl)	4.13 ± 0.50	0.001	3.71 ± 0.49
Abnormal albumin (<3.5 g/dl)	12 (9%)	0.001	21 (36%)
Prothrombin time (INR)	1.09 ± 0.10	0.001	1.18 ± 0.12
Abnormal INR (> 1.2)	7 (7%)	0.001	19 (36%)
HCC Diameter (mm)	28.3 ± 10.9	NS	28.5 ± 11.1
Edmondson–Steiner's classification (I-II; III-IV)	143; 9 (94%; 6%)	NS	53; 6 (90%; 10%)
Vascular invasion (present)	49 (32%)	NS	14 (23%)
AFP > 20ng/dl	50 (31%)	NS	19 (30%)

MELD, model for end-stage liver disease; BCLC, Barcelona Clinic Liver Cancer; INR, international normalized ratio; HCC, hepatocellular carcinoma.