Table 4.
The results of univariate and multivariate analysis of the influence of pre- and intra-operative factors on the survival rates among the 223 patients with hepatocellular carcinoma (HCC) included in the present study
| Variables | Univariate analysis (P) | Hazard ratio | 95% CI | P |
|---|---|---|---|---|
| Aetiology (HCV versus other) | NS | |||
| BCLC (A1; A2; A3) | NS | |||
| Child-Pugh (A5 versus A6) | 0.008 | 1.540 | 0.840–2.825 | 0.162 |
| MELD (<9 versus > 9) | NS | |||
| HR (Laparoscopic versus laparotomy) | NS | |||
| HCC diameter (< versus >20 mm) | 0.009 | 1.609 | 0.902–2.869 | 0.107 |
| Edmondson classification (I-II versus III-IV) | 0.004 | 1.996 | 0.615–6.477 | 0.250 |
| Vascular invasion (absent versus present) | NS | |||
| Portal hypertension | 0.021 | 1.696 | 0.887–3.245 | 0.110 |
| INR (normal versus abnormal) | NS | |||
| Bilirubin (normal versus abnormal) | NS | |||
| Albumin (normal versus abnormal) | 0.001 | 2.204 | 1.088–4.463 | 0.028 |
| AST (normal versus abnormal) | NS | |||
| Creatinine (normal versus abnormal) | 0.039 | 1.671 | 0.615–4.539 | 0.314 |
| AFP (normal versus abnormal) | 0.030 | 1.650 | 0.929–2.929 | 0.087 |
BCLC, Barcelona Clinic Liver Cancer; MELD, model for end-stage liver disease; HR, hepatic resction; INR, international normalized ratio; AST, aspartate transaminase; AFP, alpha-fetoprotein; NS, not significant.