Table 3.
Independent determinants of plasma ADMA concentrations in acute ischemic stroke patients
| Time point | Parameters | β | SE | P value |
|---|---|---|---|---|
| 6 h | TIMP-1 | 0.412 | 0.001 | 0.002 |
| 12 h | MMP-9 | −0.350 | 0.000 | 0.029 |
| 24 h | TIMP-1 | 0.426 | 0.000 | 0.002 |
| 3 days | TIMP-1 | 0.452 | 0.000 | 0.001 |
| 7 days | IL-6 | 0.629 | 0.003 | 0.000 |
| NIHSS 2-8 | 0.411 | 0.035 | 0.002 | |
| NIHSS >8 | 0.159 | 0.041 | 0.216 |
Multiple stepwise linear regression analysis adjusted for age, gender, and stroke severity at admission. ADMA, asymmetric dimethylarginine; IL-6, interleukin-6; MMP-9, matrix metalloproteinase-9; NIHSS, National Institutes of Health Stroke Scale; TIMP-1, tissue inhibitor of matrix metalloproteinase-1.