Table 4.
Independent determinants of plasma SDMA concentrations in acute ischemic stroke patients
| Time point | Parameters | β | SE | P value |
|---|---|---|---|---|
| 6 h | MCP-1 | 0.365 | 0.000 | 0.002 |
| eGFR baseline | −0.486 | 0.001 | 0.000 | |
| 12 h | eGFR baseline | −0.493 | 0.001 | 0.000 |
| 24 h | MCP-1 | 0.301 | 0.000 | 0.014 |
| eGFR baseline | −0.353 | 0.001 | 0.004 | |
| 3 days | IL-6 | 0.336 | 0.005 | 0.005 |
| MCP-1 | 0.282 | 0.000 | 0.016 | |
| eGFR baseline | −0.359 | 0.001 | 0.003 | |
| 7 days | IL-6 | 0.505 | 0.004 | 0.000 |
| MCP-1 | 0.236 | 0.000 | 0.023 | |
| eGFR baseline | −0.316 | 0.001 | 0.003 |
Multiple stepwise linear regression analysis adjusted for age, gender, eGFR at baseline and stroke severity at admission. eGFR, estimated glomerular filtration rate; IL-6, interleukin-6; MCP-1, monocyte chemotactic protein-1; SDMA, symmetric dimethylarginine.