Figure 2.

Effects of oxPL on viability of RAW264.7 cells and BMM. RAW264.7 cells (Panel A and B) and BMM (Panel C and D) were incubated with lipid dispersions in DMEM under low serum conditions (0,1% FCS) using various lipid concentration and incubation times. Cell viabilities were determined using the MTT assay described under materials and methods. Indicated values are relative viabilities (viabilities of control cells were set 1). Results obtained with RAW264.7 cells are means of 6 replicates out of three independent experiments. Results obtained with BMM (isolated and pooled from femurs and tibias of 3 or 5 mice, see materials and methods) are means of 4 replicates out of two independent experiments. Significance was determined by Student’s t-test (two tailed, unpaired). * p ≤ 0,05, *** p ≤ 0,005.