Table 2.
Demographic characteristics and laboratory findings of adult patients with Plasmodium knowlesi malaria
| Variable | Uncomplicated malaria n = 93 | Severe malaria n = 17 | p-value |
|---|---|---|---|
|
Demographic characteristic | |||
| Age, mean (95% CI), years |
43.44 (40.4 – 46.5) |
49.59 (43.24 – 55.94) |
0.11 |
| Male sex, % |
68.8 |
70.6 |
NA |
| Iban ethnicity, % |
81.7 |
88.2 |
NA |
|
Laboratory findings at admission | |||
| White blood cell count, x 103/μl1 |
5.9 (5 – 7.55) |
8.7 (6.7 – 12.5) |
0.009 |
| Neutrophils, mean (95% CI), % |
70.4 (68.8 – 71.9) |
75.1 (69.9 – 80.4) |
0.025 |
| Monocytes, %1 |
2 (1 – 5) |
3 (2 – 4) |
0.69 |
| Lymphocytes, mean (95% CI), % |
25.2 (23.8 – 26.6) |
21.2 (16.4 – 26) |
0.034 |
| Parasite count, parasites/μl1 |
3843.5 (714.5 – 13030.5) |
94256 (18432 – 285768) |
<0.0001 |
| Parasite count, % IRBC1 |
0.3 (0.1- 0.7) |
2.5 (0.7 – 11.1) |
<0.0001 |
| Platelet count, x 103 platelets/μl1 |
69 (44 – 99) |
38 (26 – 48) |
0.0004 |
| PCN count, cells/μl1 | 36 (0–128) | 563 (158 – 1388) | <0.0001 |
1 median, interquartile range.
95% CI 95% confidence interval.
% IRBC % infected red blood cells.
PCN pigment-containing neutrophils.
NA not assessed.