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. 2012 Jun 15;11:28. doi: 10.1186/1475-925X-11-28

Figure 6.

Figure 6

Use of the shear transform, A. The desired point for MN is P. However, in this example the global minimum of the waveform is P1, which is the initial guess for MN. A shear transform of the pressure waveform between P1 and MX reveals a minimum (P2) outside the range of D, and hence the time of P2 is taken as the time of MN.