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. 2012 Dec 17;2012:981461. doi: 10.1155/2012/981461

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Copyright © 2012 Azza A. K. El-Sheikh et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of two doses of coenzyme Q10 (CoQ10) on renal caspase 3 immunohistochemical semiquantitative analysis in rats exposed to doxorubicin- (Dox-) induced nephrotoxicity. Kidneys were isolated from control untreated group, animals treated with low or high dose CoQ10 (CoQ10L or CoQ10H, resp.), and animals treated with Dox, or with Dox together with CoQ10L or CoQ10H, respectively. Values are represented as means ± SE of number of immuno-positive cells for caspase 3 in sections of 3 animals of each group, 5 fields/section. ^aSignificant difference compared with control and ^bsignificant difference compared to Dox, with significant difference from control. Significant difference is reported when P < 0.05.