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. 2012 Dec 31;7(12):e53255. doi: 10.1371/journal.pone.0053255

Figure 4. Lack of effect of diclofenac on the transient outward potassium (Ito) and on the inward rectifier potassium (IK1) currents in canine ventricular myocytes.

Figure 4

A, top: Representative Ito current traces under control conditions and after application of 50 µM diclofenac. A, bottom: Current – voltage relationships of Ito under control conditions and in the presence of 50 µM diclofenac. Panel B shows steady-state current – voltage relationships of IK1 before and after application of 50 µM diclofenac. Insets depict the voltage protocol applied during measurements. Data are expressed as mean ± SEM, n = number of measurements/number of animals.