Figure 2. Locomotor activity measured in open field test.

Distance traveled (A, B), stereotypic behavior (C), vertical activity (D), and time spent in the center area (E). Measurements are blocked in 5 min (A, C, D, and E) or in 1 min (B, shown only for the first 10 min). The Zfhx2-deficient mice were generally hyperactive but were hypoactive in the initial period in the open field.