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| Cell line | IC50 value | ||||
| irinotecan [µM] | cisplatin [µg/ml] | 5-FU [µg/ml] | paclitaxel [µM] | gemcitabine [µg/ml] | |
| HROC24P | 2.2 | 2.0 | 0.2 | <0.01 | 0.00015 |
| HROC87X | 0.9 | 1.7 | 0.8 | <0.01 | 0.002 |
| HROC113P | 12.8 | 1.3 | 1.0 | 2.8 | 0.00018 |
| plasma levels (pharmacokinetic) | 10.0 | 2.0 | 20.0 | 50.0–70.0 | 6.0 |
Values are given as mean, resulting from at least three independent experiments each performed in triplicates.
