Table 2.
Antinociceptive effect of essential oil ofTeucrium stocksianumbioss on abdominal writhing in mice indused acetic acid abdominal injection
| Dose (mg/kg) | N | Number of wriths in 20 min (mean ± S.D) | % Inhibition |
|---|---|---|---|
| Control (10 ml/kg) Essential oil |
6 |
58 ± 5.600 |
|
| 20 |
6 |
30.333 ± 2.42212 |
47.701** |
| 40 |
6 |
9.6667 ± 2.16025 |
83.333** |
| 80 |
6 |
3.5000 ± 1.64317 |
93.965** |
| 160 |
6 |
17.5000 ± 3.50714 |
69.827** |
| Diclofenic sodium | 6 | 17.3333 ± 3.55903 | 70.115** |
N: Number of animal per group. D.Sod: Diclofenic Sodium. Percent inhibition was calculated in comparison to control. F = 190.486, d.f. = 35. ED50 for analgesic effect of essential oil was 31.5 ± 1.72415 mg/kg (b.w). The significance showed by ** P ≤ 0.05.