Fig. 3.

Effects of G-CSF administration on peripheral WBC and lymphocyte reconstitution.

BALB/c mice were exposed to 6 Gy of total body irradiation and were treated with 100 μg/kg G-CSF or an identical volume of PBS (control) once daily for 14 days. Peripheral blood samples were collected, and the white blood count (WBC) (Fig. 3A), absolute lymphocyte count (ALC) (Fig. 3B), and the absolute number of CD3+ (Fig. 3C), CD4+ (Fig. 3D) and CD8+ T cells (Fig. 3E) were determined. Values represent the mean ± SD of 10 independent animals per group. *P < 0.05, **P < 0.01 compared with PBS-treated control mice.